Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation

Placental site nodule is an uncommon, benign, generally asymptomatic lesion of trophoblastic origin, which may often be detected several months to years after the tenancy from which it resulted. PSN usually presents as menorrhagia, intermenstrual bleeding or an abnormal pap smear. PSN is benign, but it is important to distinguish it from the other benign and malignant lesions like decidua, placental polyp, exaggerated placental site and placental site trophoblastic tumor and squamous cell carcinoma. Follow ups of typical PSNs do not show recurrence or malignant potential.

Gestational Trophoblastic Tumors: A Timely Review of Diagnostic Pathology - Document - Gale OneFile: Health and Medicine

Placental site nodule: A tumor like trophoblastic lesion - rare case report

Gestational Trophoblastic Disease

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The placenta, products of conception, and gestational trophoblastic disease (Chapter 40) - Silverberg's Principles and Practice of Surgical Pathology and Cytopathology