Non-Destructive Quantification of Fragmentation Within Tablets

The purpose of this study was to investigate the applicability of terahertz time-domain spectroscopy (THz-TDS) to quantify fragmentation upon tableting.
Material deformation behaviour has a critical impact on tablet formation. Fragmentation is one of the key mechanisms affecting the strength of a final compact, however, quantitative methods for estimating fragmentation are often complex, destructive

Non-destructive quantification of fragmentation within tablets after compression from scattering analysis of terahertz transmission measurements - ScienceDirect

Non-destructive quantification of fragmentation within tablets after compression from scattering analysis of terahertz transmission measurements - ScienceDirect

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Investigation of the effects of tableting parameters on reliable

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Fast and non-destructive pore structure analysis using terahertz time-domain spectroscopy - ScienceDirect

Terahertz frequency domain sensing for fast porosity measurement

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Non-destructive quantification of fragmentation within tablets after compression from scattering analysis of terahertz transmission measurements - ScienceDirect

Critical spectroscopic considerations towards reliable detection of material using terahertz time-domain spectroscopy - ScienceDirect

Summary of the numerical iteration results for the tested four tablets

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Table 1 from Detection of porosity of pharmaceutical compacts by