Non-Destructive Quantification of Fragmentation Within Tablets After Compression From Scattering Analysis of Terahertz Transmission Measurements - Pharma Excipients

The purpose of this study was to investigate the applicability of terahertz time-domain spectroscopy (THz-TDS) to quantify fragmentation upon tableting.
Material deformation behaviour has a critical impact on tablet formation. Fragmentation is one of the key mechanisms affecting the strength of a final compact, however, quantitative methods for estimating fragmentation are often complex, destructive

Pharmaceuticals, Free Full-Text

Non-destructive Determination of Disintegration Time and Dissolution in Immediate Release Tablets by Terahertz Transmission Measurements

Terahertz-Based Porosity Measurement of Pharmaceutical Tablets: a Tutorial

Investigation of the effects of tableting parameters on reliable quantitative terahertz spectroscopy

Investigation of the effects of tableting parameters on reliable quantitative terahertz spectroscopy

Investigation of Quantitative X-ray Microscopy for Assessment of API and Excipient Microstructure Evolution in Solid Dosage Processing

Terahertz detection of porosity and porous microstructure in

Pharmaceuticals, Free Full-Text

Sensors, Free Full-Text

Investigation of the effects of tableting parameters on reliable quantitative terahertz spectroscopy

Pharmaceutics, Free Full-Text

Non-destructive Determination of Disintegration Time and Dissolution in Immediate Release Tablets by Terahertz Transmission Measurements

Investigation of the effects of tableting parameters on reliable quantitative terahertz spectroscopy

Advances in terahertz time-domain spectroscopy of pharmaceutical solids: A review - ScienceDirect